Andrey Kan (Кан Андрей Владимирович)

Available student projects (last upd. 16 Sep 2016)

Reconstructing the immune response: from molecules to cells to systems

In this interdisciplinary project we will use bioinformatics methods to develop predictive mathematical models of lymphocyte responses. We will experimentally establish transcriptional profiles at different stages of the response, and interrogate these data using advanced statistical methods. For more details refer to the institute website.

Stochastic multi-object estimation

This interdisciplinary project will develop new tools for the inference of biological information from live-cell data, which facilitate analysis of experiments and speed up discovery in cell biology. The new tools provide reliable, consistent inference that requires no manual intervention and capable of processing large volumes of data in a timely manner. Three PhD scholarships available. For more details refer to the flyer.

About me


postdoctoral researcher at the Walter and Eliza Hall Institute under supervision of Phil Hodgkin at the Immunology Division

my research interests include computational immunology, medical image analysis and machine learning


BS in Telecommunications from Tashkent University of Information Technologies
MS in Computer Science from Lomonosov Moscow State University
PhD in Computer Science from The University of Melbourne
(supervisors: James Bailey and Christopher Leckie)


Stochastic Measurement Models for Quantifying Lymphocyte Responses Using Flow Cytometry PLoS One, 2016, vol.11 (1), e0146227, Kan A., Pavlyshyn D., Markham J.F., Dowling M.R., et al. paper Ranking cell tracking systems without manual validation Pattern Recognition Letters, 2015, vol.53, pp.38–43, Kan A., Markham J., Chakravorty R., Bailey J., and Leckie C. paper Multi-Modal Segmentation for Quantifying Fluorescent Cell Cycle Indicators Throughout Clonal Development BioImage Informatics Conference 2015, Mankowski W.C., ... , Kan A., ... , and Cohen A.R. paper Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion Science, 2014, vol.346 (6213), pp.1123–1127 Marchingo J.M., Kan A., Sutherland R.M., Duffy K.R., et al. paper    code Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility Cellular microbiology, 2014, vol.16 (5), pp.734–750 Kan A.*, Tan Y.H.*, et al. (these authors contributed equally) paper    code Stretched cell cycle model for proliferating lymphocytes Proceedings of the National Academy of Sciences, 2014, vol.111-17, pp.6377–6382 Dowling M.R.*, Kan A.*, et al. (these authors contributed equally) paper    code Evaluating spectral unmixing quality in the absence of reference objects for time lapse fluorescence microscopy IEEE International Conference on Data Mining (ICDM) Workshop on Data Mining in Medical Imaging, 2014 Liu L., Kan A., Zhou J.H.S., Markham J., et al. paper Mechanisms of cell division as regulators of acute immune response Systems and Synthetic Biology, 2014, vol.8 (3), pp.215–221 Kan A., and Hodgkin P.D. paper Measures for Ranking Cell Trackers without Manual Validation Pattern Recognition, 2013, vol.46 (11), pp.2849–2859 Kan A., Leckie C., Bailey J., Markham J., and Chakravorty R. paper    supporting page A Time Decoupling Approach for Studying Forum Dynamics World Wide Web, 2013, vol.15 (5), pp.595–620 Kan A., Chan J., Hayes C., Hogan B., Bailey J., and Leckie C. pre-print on arXiv    supplementary text Discovering Latent Blockmodels in Sparse and Noisy Graphs using Non-Negative Matrix Factorisation 22-nd ACM International Conference on Information and Knowledge Management (CIKM 2013) Chan J., Liu W., Kan A., Leckie C., Bailey J., and Ramamohanarao K. paper On Compressing Weighted Time-evolving Graphs 21-st ACM International Conference on Information and Knowledge Management (CIKM 2012) Liu W., Kan A., Chan J., Bailey J., Leckie C., Pei J., and Kotagiri R. 4 page abstract Automated and Semi-automated Cell Tracking: Addressing Portability Challenges Journal of Microscopy, 2011, vol.244 (2), pp.194–213, Kan A., Chakravorty R., Bailey J., Leckie C., Markham J., and Dowling M.R. paper    supplementary text    code (MATLAB) Studying Forum Dynamics from a User Engagement Perspective 3-rd International Conference on Web Science (WebSci 2011), Kan A., Chan J., Hayes C., and Hogan B. poster    2 page abstract A Query Based Approach for Mining Evolving Graphs 8-th Australasian Data Mining Conference (AusDM 2009), vol. 101, Kan A., Chan J., Bailey J., and Leckie C. paper    presentation slides    code (C++) Video Decoding Method and Apparatus U.S. Patent No: 2009/0052542 A1 Assignee: Samsung Electronics Co., Ltd. Romanovskiy A., and Kan A. on Google Patents

PhD Thesis: Automated Analysis of Time Lapse Microscopy Images
(final version submitted in January 2013)
In this thesis, we focus on cell tracking systems. We develop methods to reduce the amount of manual work while maintaining a satisfactory level of accuracy of cell tracking systems.
thesis    supporting page


A video that shows an amazing tri-division of B cells. Here is an unofficial version of BibTeX style (.bst file) for Journal of Microscopy. This style was created using makebst and manual editions. Here is a LaTeX template for a generic Computer Science paper (and here is a version for Lyx). My favorite songs can be broadly categorized into energetic music and soft music.

Grab a candy and come again :)

Phone: +61 3 9345 2596 Level 3W, 1G Royal Parade, Parkville VIC 3052
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This website was last time modified in December 2015